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Heartburn

MESH PheWeb

R18_HEARTBURN

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 R12
Cause of death: ICD-10 R12

2544

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2544

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Check minimum number of events None

2544

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Include endpoints None

2544

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R18_HEARTBURN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 R1
Name in latin Pyrosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2544 1563 981
Unadjusted prevalence (%) 0.72 0.79 0.62
Mean age at first event (years) 56.80 55.61 58.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.19 [1.20, 4.00] 1.1e-2 150
15 years 0.01 0.87 [0.52, 1.48] 6.1e-1 47
5 years 0.00 3.35 [2.16, 5.19] 6.5e-8 69
1 year 0.00 7.17 [4.34, 11.87] 1.7e-14 28

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_HEARTBURN – Heartburn
GWS hits:

Survival analyses between endpoints

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Plot

before Heartburn
after Heartburn

loading spinner Loading survival analyses plot