Other symptoms and signs involving the nervous and musculoskeletal systems

MESH PheWeb

R18_OTHER_SYMPTOMS_SIGNS_INVOLVI_NERVOUS_MUSCULOS_SYSTEMS

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

Apply sex-specific rule None

356077

Check conditions None

356077

Filter registries

Hospital Discharge: ICD-10 R29

Cause of death: ICD-10 R29

13255

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

13255

Check minimum number of events None

13255

Include endpoints None

13255

R18_OTHER_SYMPTOMS_SIGNS_INVOLVI_NERVOUS_MUSCULOS_SYSTEMS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R2[5-9]

Name in latin Alia symptomata et signa ad systema nervosum et systema musculosceletale pertinentia

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Similar endpoints

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List of similar endpoints to Other symptoms and signs involving the nervous and musculoskeletal systems based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

13255

8134

5121

Unadjusted prevalence (%)

3.73

4.10

3.25

Mean age at first event (years)

51.61

48.52

56.51

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	2.75 [1.96, 3.87]	5.6e-9	1139
15 years	0.01	1.50 [1.13, 2.01]	5.5e-3	448
5 years	0.00	3.44 [2.78, 4.26]	8.7e-30	378
1 year	0.00	9.63 [7.73, 11.99]	2.5e-91	215

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_OTHER_SYMPTOMS_SIGNS_INVOLVI_NERVOUS_MUSCULOS_SYSTEMS – Other symptoms and signs involving the nervous and musculoskeletal systems
GWS hits:

Survival analyses between endpoints

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Plot

before Other symptoms and signs involving the nervous and musculoskeletal systems
after Other symptoms and signs involving the nervous and musculoskeletal systems

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Table

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Drugs most likely to be purchased after Other symptoms and signs involving the nervous and musculoskeletal systems

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≡ Risteys

R8

R7

R6

R5

R4

R3

Other symptoms and signs involving the nervous and musculoskeletal systems

Endpoint definition

Upset plot

Case counts by code for Other symptoms and signs involving the nervous and musculoskeletal systems (R18_OTHER_SYMPTOMS_SIGNS_INVOLVI_NERVOUS_MUSCULOS_SYSTEMS)

Similar endpoints

Summary Statistics

Key figures

Number of individuals

Unadjusted prevalence

Mean age at first event

Follow-up

Absolute risk

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Number of individuals (N)

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Authentication required

Survival analyses between endpoints

Plot

Table

Drugs most likely to be purchased after Other symptoms and signs involving the nervous and musculoskeletal systems