Codeine or tramadol medication

RX_CODEINE_TRAMADOL

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79

144835

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Check pre-conditions, main-only, mode, ICD version None

50351

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Check minimum number of events

Min. number of events 3

50351

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Include endpoints None

50351

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RX_CODEINE_TRAMADOL

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 50351 29418 20933
Unadjusted prevalence (%) 14.15 14.83 13.30
Mean age at first event (years) 54.41 52.52 57.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.92 [2.59, 3.29] 4.6e-68 3642
15 years 0.01 1.71 [1.52, 1.93] 5.3e-18 2056
5 years 0.00 3.02 [2.71, 3.37] 4.9e-89 1325
1 year 0.00 3.23 [2.75, 3.81] 2.4e-45 255

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication
GWS hits: 7

Survival analyses between endpoints

Plot

before Codeine or tramadol medication
after Codeine or tramadol medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Codeine or tramadol medication