Codeine or tramadol medication

RX_CODEINE_TRAMADOL

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79

144835

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Check pre-conditions, main-only, mode, ICD version None

50351

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Check minimum number of events

Min. number of events 3

50351

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Include endpoints None

50351

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RX_CODEINE_TRAMADOL

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 50351 29418 20933
Unadjusted prevalence (%) 14.15 14.83 13.30
Mean age at first event (years) 54.41 52.52 57.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.92 [2.59, 3.29] 4.6e-68 3642
15 years 0.01 1.71 [1.52, 1.93] 5.3e-18 2056
5 years 0.00 3.02 [2.71, 3.37] 4.9e-89 1325
1 year 0.00 3.23 [2.75, 3.81] 2.4e-45 255

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication
GWS hits: 7

Survival analyses between endpoints

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Plot

before Codeine or tramadol medication
after Codeine or tramadol medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Codeine or tramadol medication

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