≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

First line medication for Crohns disease

PheWeb

RX_CROHN_1STLINE

No definition available.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Medicine purchases: ATC A07EC|H02AB

139292

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

68486

diagram downward connector
diagram bullet

Check minimum number of events

Min. number of events 3

68486

diagram downward connector

Include endpoints None

68486

diagram downward connector
RX_CROHN_1STLINE

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 68486 40229 28257
Unadjusted prevalence (%) 19.25 20.28 17.96
Mean age at first event (years) 50.55 47.45 54.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.33 [2.11, 2.56] 9.1e-68 10022
15 years 0.01 1.46 [1.34, 1.59] 1.3e-17 4131
5 years 0.00 3.30 [3.07, 3.56] <1e-100 2897
1 year 0.00 6.06 [5.43, 6.76] <1e-100 1033

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: RX_CROHN_1STLINE – First line medication for Crohns disease
GWS hits: 27

Survival analyses between endpoints

↥

Plot

before First line medication for Crohns disease
after First line medication for Crohns disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after First line medication for Crohns disease

↥