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Second line medication for Crohns disease

PheWeb

RX_CROHN_2NDLINE

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC L04AX|L01BB02

21234

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Check pre-conditions, main-only, mode, ICD version None

17784

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Check minimum number of events

Min. number of events 3

17784

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Include endpoints None

17784

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RX_CROHN_2NDLINE

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 17784 11068 6716
Unadjusted prevalence (%) 5.00 5.58 4.27
Mean age at first event (years) 50.35 49.33 52.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.88 [2.38, 3.50] 5.0e-27 1138
15 years 0.01 1.89 [1.57, 2.28] 1.4e-11 592
5 years 0.00 3.48 [2.94, 4.12] 1.4e-47 362
1 year 0.00 3.80 [2.90, 4.97] 3.0e-22 72

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_CROHN_2NDLINE – Second line medication for Crohns disease
GWS hits: 26

Survival analyses between endpoints

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Plot

before Second line medication for Crohns disease
after Second line medication for Crohns disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Second line medication for Crohns disease

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