Methotrexate

RX_L01BA01

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC L01BA01

5988

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Check pre-conditions, main-only, mode, ICD version None

4913

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Check minimum number of events

Min. number of events 3

4913

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Include endpoints None

4913

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RX_L01BA01

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 4913 3429 1484
Unadjusted prevalence (%) 1.38 1.73 0.94
Mean age at first event (years) 46.90 45.57 49.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.91 [1.46, 2.51] 2.5e-6 522
15 years 0.01 1.42 [1.14, 1.78] 2.0e-3 239
5 years 0.00 1.80 [1.41, 2.29] 2.4e-6 86
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_L01BA01 – Methotrexate
GWS hits:

Survival analyses between endpoints

Plot

before Methotrexate
after Methotrexate

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