Tumor necrosis factor alpha inhibitors

RX_L04AB

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Medicine purchases: ATC L04AB

3370

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

3216

diagram downward connector
diagram bullet

Check minimum number of events

Min. number of events 3

3216

diagram downward connector
RX_L04AB

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 3216 2019 1197
Unadjusted prevalence (%) 0.90 1.02 0.76
Mean age at first event (years) 46.29 45.87 47.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.61 [0.73, 3.52] 2.4e-1 60
15 years 0.01 1.13 [0.50, 2.51] 7.7e-1 42
5 years 0.00 1.07 [0.48, 2.36] 8.7e-1 12
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_L04AB – Tumor necrosis factor alpha inhibitors
GWS hits:

Survival analyses between endpoints

Plot

before Tumor necrosis factor alpha inhibitors
after Tumor necrosis factor alpha inhibitors

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Tumor necrosis factor alpha inhibitors