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L04AD Calcineurin inhibitors

PheWeb

RX_L04AD

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC L04AD

3099

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Check pre-conditions, main-only, mode, ICD version None

2733

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Check minimum number of events

Min. number of events 3

2733

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Include endpoints None

2733

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RX_L04AD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 2733 1355 1378
Unadjusted prevalence (%) 0.77 0.68 0.88
Mean age at first event (years) 48.56 47.49 49.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 9.30 [4.74, 18.26] 8.8e-11 195
15 years 0.03 4.60 [2.31, 9.16] 1.4e-5 96
5 years 0.01 11.12 [6.45, 19.16] 4.0e-18 79
1 year 0.00 15.62 [8.22, 29.65] 4.4e-17 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_L04AD – L04AD Calcineurin inhibitors
GWS hits:

Survival analyses between endpoints

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Plot

before L04AD Calcineurin inhibitors
after L04AD Calcineurin inhibitors

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after L04AD Calcineurin inhibitors

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