SLE, strict definition

SLE_STRICT

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

903

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SLE_STRICT

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 903 754 149
Unadjusted prevalence (%) 0.25 0.38 0.09
Mean age at first event (years) 46.89 45.91 51.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.59 [1.69, 7.64] 8.9e-4 79
15 years 0.02 2.31 [1.23, 4.33] 9.1e-3 35
5 years 0.01 4.19 [2.20, 7.97] 1.3e-5 19
1 year 0.00 12.90 [6.24, 26.65] 4.9e-12 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: SLE_STRICT – SLE, strict definition
GWS hits: 8

Survival analyses between endpoints

Plot

before SLE, strict definition
after SLE, strict definition

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Drugs most likely to be purchased after SLE, strict definition