Selective serotonin reuptake inhibitors

SSRI

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC N06AB

93542

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Check pre-conditions, main-only, mode, ICD version None

69748

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Check minimum number of events

Min. number of events 3

69748

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Include endpoints None

69748

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SSRI

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 69748 47050 22698
Unadjusted prevalence (%) 19.60 23.71 14.42
Mean age at first event (years) 42.66 40.83 46.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.81 [1.59, 2.05] 1.1e-19 6181
15 years 0.01 1.38 [1.24, 1.54] 8.1e-9 2836
5 years 0.00 2.57 [2.35, 2.82] 1.6e-92 1606
1 year 0.00 2.60 [2.25, 3.00] 4.2e-38 319

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SSRI – Selective serotonin reuptake inhibitors
GWS hits:

Survival analyses between endpoints

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Plot

before Selective serotonin reuptake inhibitors
after Selective serotonin reuptake inhibitors

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Selective serotonin reuptake inhibitors

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