Selective serotonin reuptake inhibitors

SSRI

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC N06AB

93542

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Check pre-conditions, main-only, mode, ICD version None

69748

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Check minimum number of events

Min. number of events 3

69748

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Include endpoints None

69748

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SSRI

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 69748 47050 22698
Unadjusted prevalence (%) 19.60 23.71 14.42
Mean age at first event (years) 42.66 40.83 46.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.81 [1.59, 2.05] 1.1e-19 6181
15 years 0.01 1.38 [1.24, 1.54] 8.1e-9 2836
5 years 0.00 2.57 [2.35, 2.82] 1.6e-92 1606
1 year 0.00 2.60 [2.25, 3.00] 4.2e-38 319

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: SSRI – Selective serotonin reuptake inhibitors
GWS hits:

Survival analyses between endpoints

Plot

before Selective serotonin reuptake inhibitors
after Selective serotonin reuptake inhibitors

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Selective serotonin reuptake inhibitors