Respiratory tuberculosis

TBC_RESP

pulmonary tuberculosis: A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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TBC_RESP

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Respiratory tuberculosis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1687 559 1128
Unadjusted prevalence (%) 0.47 0.28 0.72
Mean age at first event (years) 47.63 40.41 51.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.27 [1.81, 2.84] 1.5e-12 617
15 years 0.01 1.47 [1.24, 1.75] 1.2e-5 265
5 years 0.00 2.42 [2.00, 2.93] 4.5e-20 140
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: TBC_RESP – Respiratory tuberculosis
GWS hits: 1

Survival analyses between endpoints

Plot

before Respiratory tuberculosis
after Respiratory tuberculosis

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Drugs most likely to be purchased after Respiratory tuberculosis