Diseases of the respiratory system

X_RESPIRATORY

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J00-J06, J09-J18, J20-J22, J30-J39, J40-J47, J60-J70, J80-J84, J85-J86, J90-J94, J95-J99
Hospital discharge: ICD-9 4[6-9]|5[0-1]
Hospital discharge: ICD-8 4[6-9]|5[0-1]
Cause of death: ICD-9 4[6-9]|5[0-1]
Cause of death: ICD-8 4[6-9]|5[0-1]

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

184341

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X_RESPIRATORY

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 184341 94560 89781
Unadjusted prevalence (%) 51.81 47.66 57.05
Mean age at first event (years) 38.99 36.33 41.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 4.51 [4.23, 4.81] <1e-100 24255
15 years 0.01 2.59 [2.42, 2.77] <1e-100 7922
5 years 0.01 5.21 [4.88, 5.57] <1e-100 6035
1 year 0.01 24.56 [22.01, 27.41] <1e-100 6352

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: X_RESPIRATORY – Diseases of the respiratory system
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the respiratory system
after Diseases of the respiratory system

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Drugs most likely to be purchased after Diseases of the respiratory system