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Family history of certain disabilities and chronic diseases leading to disablement

MESH PheWeb

Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 Z82
Cause of death: ICD-10 Z82

1060

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1060

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Check minimum number of events None

1060

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Include endpoints None

1060

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Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 Z[8-9]

Similar endpoints

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List of similar endpoints to Family history of certain disabilities and chronic diseases leading to disablement based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1060 791 269
Unadjusted prevalence (%) 0.30 0.40 0.17
Mean age at first event (years) 41.86 40.28 46.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.07 [1.71, 9.68] 1.5e-3 20
15 years 0.02 2.19 [0.82, 5.85] 1.2e-1 10
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL – Family history of certain disabilities and chronic diseases leading to disablement
GWS hits:

Survival analyses between endpoints

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Plot

before Family history of certain disabilities and chronic diseases leading to disablement
after Family history of certain disabilities and chronic diseases leading to disablement

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Drugs most likely to be purchased after Family history of certain disabilities and chronic diseases leading to disablement

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