Condition for Implicit Sepsis (Organ dysfunction codes)

AB1_SEPSIS_CONDITION

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D65|D695|E872|G934|I46|I959|J80|J952|J96|J960|J969|K720|K729|N00|N17|R090|R092|R400|R401|R402|R418|R55|R57
Hospital discharge: ICD-9 2762A|2866A|2874A|2874X|3483X|4275A|4589X|5185A|570|5722A|580|584|7800A|7802X|7855A|7855X|7991A
Cause of death: ICD-10 D65|D695|E872|G934|I46|I959|J80|J952|J96|J960|J969|K720|K729|N00|N17|R090|R092|R400|R401|R402|R418|R55|R57
Cause of death: ICD-9 2762A|2866A|2874A|2874X|3483X|4275A|4589X|5185A|570|5722A|580|584|7800A|7802X|7855A|7855X|7991A

36152

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 9 ; C.O.D: 10, 9

35851

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Check minimum number of events None

35851

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Include endpoints None

35851

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AB1_SEPSIS_CONDITION

Extra metadata

First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 35851 16387 19464
Unadjusted prevalence (%) 10.08 8.26 12.37
Mean age at first event (years) 61.81 58.58 64.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.77 [5.12, 6.51] <1e-100 8699
15 years 0.01 2.13 [1.90, 2.38] 2.6e-38 2244
5 years 0.01 5.43 [4.98, 5.92] <1e-100 2803
1 year 0.01 25.61 [23.23, 28.23] <1e-100 3338

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AB1_SEPSIS_CONDITION – Condition for Implicit Sepsis (Organ dysfunction codes)
GWS hits:

Survival analyses between endpoints

Plot

before Condition for Implicit Sepsis (Organ dysfunction codes)
after Condition for Implicit Sepsis (Organ dysfunction codes)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Condition for Implicit Sepsis (Organ dysfunction codes)