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Implicit Sepsis

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AB1_SEPSIS_IMPLICIT

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

AB1_SEPSIS_CONDITION

35851

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Filter registries

Hospital Discharge: ICD-10 A0[0-9]|A19|A2[0-8]|A3[0-2]|A3[6-9]|A4[2-9]|A54|A59|A690|A691|A699|A70|A7[4-9]|A8[0-1]|A8[3-9]|A9[2-9]|B0[0-6]|B0[89]|B2[5-7]|B3[34]|B3[7-9]|B4[0-6]|B4[89]|B50|B5[45]|B5[7-9]|B60|B64|B67|B9[5-7]|B99|G0[0-8]|H050|H602|H700|I00|I33|I3[89]|I400|R02|J0[1-9]|J1[0-8]|J2[0-2]|J36|J39[01]|J8[56]|K3[567]|K57|K61|K63[01]|K65|K750|K810|K812|K830|L0[2-4]|L08|M0[01]|M86|N10|N151|N30|N390|N41[023]|N45|N7[0-4]|N980|O030|O035|O045|O080|O23|O753|O86|O883|O91|O98|T802|T814|T826|T827|T835|T836|T845|T846[0246]|T847|T857|T880|U04
Hospital discharge: ICD-9 00[1-9]|018|02[0-7]|03[0-6]|039|04[0-1]|04[5-9]|05[0-7]|06[0-6]|3483X|4275A|4589X|5185A|570|5722A|580|584|7800A|7802X|7855A|7855X|7991A|07[2-5]|0770A|0779X|07[89]|08[0-6]|088|098|10[01]|1049X|112|11[4-8]|122|13[0-1]|136|320|32[2-5]|3760A|3801C|3830A|390|421|4249X|46[1-6]|475|4782[AB]|48[0-5]|487|510|513|54[0-2]|562|56[67]|5695A|5698A|5720A|5750A|5751A|5761|590|595|5990|6010A|6012A|6013A|604|614|615|616|6342A|6351|6391A|6466A|647|6593B|670|672|6733|675|68[0-3]|686|711|730|7854A|7907A|7908A|9966A|9985A|9993A
Hospital discharge: excluded ICD-10 A021|A217|A227|A241|A282|A327|A427|A548|B007|B377
Hospital discharge: excluded ICD-9 0031A|0223A|0545A|1125A
Cause of death: ICD-10 A0[0-9]|A19|A2[0-8]|A3[0-2]|A3[6-9]|A4[2-9]|A54|A59|A690|A691|A699|A70|A7[4-9]|A8[0-1]|A8[3-9]|A9[2-9]|B0[0-6]|B0[89]|B2[5-7]|B3[34]|B3[7-9]|B4[0-6]|B4[89]|B50|B5[45]|B5[7-9]|B60|B64|B67|B9[5-7]|B99|G0[0-8]|H050|H602|H700|I00|I33|I3[89]|I400|R02|J0[1-9]|J1[0-8]|J2[0-2]|J36|J39[01]|J8[56]|K3[567]|K57|K61|K63[01]|K65|K750|K810|K812|K830|L0[2-4]|L08|M0[01]|M86|N10|N151|N30|N390|N41[023]|N45|N7[0-4]|N980|O030|O035|O045|O080|O23|O753|O86|O883|O91|O98|T802|T814|T826|T827|T835|T836|T845|T846[0246]|T847|T857|T880|U04
Cause of death: ICD-9 00[1-9]|018|02[0-7]|03[0-6]|039|04[0-1]|04[5-9]|05[0-7]|06[0-6]|3483X|4275A|4589X|5185A|570|5722A|580|584|7800A|7802X|7855A|7855X|7991A|07[2-5]|0770A|0779X|07[89]|08[0-6]|088|098|10[01]|1049X|112|11[4-8]|122|13[0-1]|136|320|32[2-5]|3760A|3801C|3830A|390|421|4249X|46[1-6]|475|4782[AB]|48[0-5]|487|510|513|54[0-2]|562|56[67]|5695A|5698A|5720A|5750A|5751A|5761|590|595|5990|6010A|6012A|6013A|604|614|615|616|6342A|6351|6391A|6466A|647|6593B|670|672|6733|675|68[0-3]|686|711|730|7854A|7907A|7908A|9966A|9985A|9993A
Cause of death: excluded ICD-10 A021|A217|A227|A241|A282|A327|A427|A548|B007|B377
Cause of death: excluded ICD-9 0031A|0223A|0545A|1125A

27968

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 9 ; C.O.D: 10, 9

26753

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Check minimum number of events None

26753

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Include endpoints None

26753

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AB1_SEPSIS_IMPLICIT

Extra metadata

First used in FinnGen datafreeze DF8

Summary Statistics

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Key figures

All Female Male
Number of individuals 26753 12059 14694
Unadjusted prevalence (%) 7.52 6.08 9.34
Mean age at first event (years) 56.82 53.04 59.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.01 [2.68, 3.39] 8.0e-75 7363
15 years 0.01 1.68 [1.52, 1.86] 1.4e-23 2944
5 years 0.00 3.04 [2.80, 3.31] <1e-100 1898
1 year 0.00 10.61 [9.55, 11.79] <1e-100 1346

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_SEPSIS_IMPLICIT – Implicit Sepsis
GWS hits:

Survival analyses between endpoints

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Plot

before Implicit Sepsis
after Implicit Sepsis

loading spinner Loading survival analyses plot