Acute alcohol intoxication

ALCOHOLACUTE10

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 F10.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F10.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

5770

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5770

diagram downward connector

Check minimum number of events None

5770

diagram downward connector

Include endpoints None

5770

diagram downward connector
ALCOHOLACUTE10

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10

Summary Statistics

Key figures

All Female Male
Number of individuals 5770 2027 3743
Unadjusted prevalence (%) 1.62 1.02 2.38
Mean age at first event (years) 49.04 42.57 52.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 10.57 [7.49, 14.91] 4.4e-41 1187
15 years 0.02 3.45 [2.55, 4.68] 1.1e-15 269
5 years 0.01 9.14 [7.16, 11.67] 1.9e-70 250
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ALCOHOLACUTE10 – Acute alcohol intoxication
GWS hits:

Survival analyses between endpoints

Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute alcohol intoxication