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Acute alcohol intoxication

DOID EFO MESH SNOMED PheWeb

ALCOHOLACUTE10

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F10.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F10.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

5770

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5770

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Check minimum number of events None

5770

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Include endpoints None

5770

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ALCOHOLACUTE10

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10

Summary Statistics

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Key figures

All Female Male
Number of individuals 5770 2027 3743
Unadjusted prevalence (%) 1.62 1.02 2.38
Mean age at first event (years) 49.04 42.57 52.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 10.57 [7.49, 14.91] 4.4e-41 1187
15 years 0.02 3.45 [2.55, 4.68] 1.1e-15 269
5 years 0.01 9.14 [7.16, 11.67] 1.9e-70 250
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ALCOHOLACUTE10 – Acute alcohol intoxication
GWS hits:

Survival analyses between endpoints

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Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

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Drugs most likely to be purchased after Acute alcohol intoxication

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