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Mental and behavioural disorders due to alcohol

DOID EFO MESH SNOMED PheWeb

F5_ALCOHOL

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F10
Hospital discharge: ICD-9 303|291
Hospital discharge: ICD-8 291
Hospital discharge: excluded ICD-10 F10.0
Cause of death: ICD-10 F10
Cause of death: ICD-9 303|291
Cause of death: ICD-8 291
Cause of death: excluded ICD-10 F10.1

16499

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

15382

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Check minimum number of events None

15382

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Include endpoints

18863

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F5_ALCOHOL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu alcohol

Similar endpoints

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List of similar endpoints to Mental and behavioural disorders due to alcohol based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

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Key figures

All Female Male
Number of individuals 18863 6016 12847
Unadjusted prevalence (%) 5.30 3.03 8.16
Mean age at first event (years) 45.45 40.74 47.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.83 [4.00, 5.83] 2.1e-60 3786
15 years 0.02 2.98 [2.60, 3.42] 4.4e-55 1478
5 years 0.01 4.93 [4.42, 5.51] <1e-100 829
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_ALCOHOL – Mental and behavioural disorders due to alcohol
GWS hits:

Survival analyses between endpoints

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Plot

before Mental and behavioural disorders due to alcohol
after Mental and behavioural disorders due to alcohol

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Drugs most likely to be purchased after Mental and behavioural disorders due to alcohol

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