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Malignant neoplasm of breast, HER-negative

PheWeb

C3_BREAST_HERNEG

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions

not RX_HERPLUS

190086

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Filter registries

Cause of death: ICD-10 C50
Cause of death: ICD-9 174
Cause of death: ICD-8 174
Cancer registry: Topography ICD-O-3 C50

5223

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

5223

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Check minimum number of events None

5223

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Include endpoints None

5223

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C3_BREAST_HERNEG

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 5223 5223 -
Unadjusted prevalence (%) 1.47 2.63 -
Mean age at first event (years) 56.98 56.98 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.17 [0.87, 1.58] 2.9e-1 632
15 years 0.01 0.72 [0.56, 0.94] 1.7e-2 227
5 years 0.00 2.03 [1.60, 2.57] 4.2e-9 176
1 year 0.00 5.32 [4.02, 7.04] 1.9e-31 91

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_BREAST_HERNEG – Malignant neoplasm of breast, HER-negative
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm of breast, HER-negative
after Malignant neoplasm of breast, HER-negative

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Malignant neoplasm of breast, HER-negative

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