Malignant neoplasm, wide definition for exclusion

C3_CANCER_WIDE

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 C
Hospital discharge: ICD-9 1[4-9]|20
Hospital discharge: ICD-8 1[4-9]|20
Cause of death: ICD-10 C
Cause of death: ICD-9 1[4-9]|20
Cause of death: ICD-8 1[4-9]|20
KELA reimbursements: KELA codes 115|116

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 1
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 85682 42877 42805
Unadjusted prevalence (%) 24.08 21.61 27.20
Mean age at first event (years) 61.73 57.67 65.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.12 [3.81, 4.46] <1e-100 18450
15 years 0.01 1.84 [1.69, 2.00] 2.8e-44 5420
5 years 0.01 5.72 [5.34, 6.13] <1e-100 5564
1 year 0.00 27.48 [24.67, 30.60] <1e-100 5835

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_CANCER_WIDE – Malignant neoplasm, wide definition for exclusion
GWS hits:

Survival analyses between endpoints

Plot

before Malignant neoplasm, wide definition for exclusion
after Malignant neoplasm, wide definition for exclusion

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Drugs most likely to be purchased after Malignant neoplasm, wide definition for exclusion