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Malignant neoplasm of cervix uteri

DOID EFO MESH SNOMED PheWeb

C3_CERVIX_UTERI

cervical carcinoma: A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Cause of death: ICD-10 C53
Cause of death: ICD-9 180
Cause of death: ICD-8 180
Cancer registry: Topography ICD-O-3 C53

3042

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

3042

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Check minimum number of events None

3042

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Include endpoints None

3042

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C3_CERVIX_UTERI

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

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Key figures

All Female Male
Number of individuals 3042 3042 -
Unadjusted prevalence (%) 0.86 1.53 -
Mean age at first event (years) 37.33 37.33 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.75 [1.21, 2.52] 3.0e-3 145
15 years 0.01 0.74 [0.50, 1.10] 1.4e-1 38
5 years 0.00 2.40 [1.56, 3.69] 7.0e-5 38
1 year 0.00 3.42 [1.71, 6.85] 5.2e-4 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_CERVIX_UTERI – Malignant neoplasm of cervix uteri
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm of cervix uteri
after Malignant neoplasm of cervix uteri

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Drugs most likely to be purchased after Malignant neoplasm of cervix uteri

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