Malignant neoplasm of corpus uteri

C3_CORPUS_UTERI

endometrial carcinoma: A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Cause of death: ICD-10 C54
Cause of death: ICD-9 182
Cause of death: ICD-8 1820
Cancer registry: Topography ICD-O-3 C54

1728

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

1728

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Check minimum number of events None

1728

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Include endpoints None

1728

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C3_CORPUS_UTERI

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 1728 1728 -
Unadjusted prevalence (%) 0.49 0.87 -
Mean age at first event (years) 63.75 63.75 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.51 [1.66, 3.80] 1.3e-5 293
15 years 0.01 1.17 [0.84, 1.63] 3.6e-1 94
5 years 0.01 3.47 [2.53, 4.75] 1.1e-14 96
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_CORPUS_UTERI – Malignant neoplasm of corpus uteri
GWS hits:

Survival analyses between endpoints

Plot

before Malignant neoplasm of corpus uteri
after Malignant neoplasm of corpus uteri

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Drugs most likely to be purchased after Malignant neoplasm of corpus uteri