Malignant neoplasm of heart, mediastinum and pleura

C3_HEART_MEDIASTINUM_PLEURA

Heart neoplasm: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Cause of death: ICD-10 C38
Cause of death: ICD-9 16[3-4]
Cause of death: ICD-8 163[0-1]
Cause of death: excluded ICD-9 1640
Cancer registry: Topography ICD-O-3 C38

238

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

238

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Check minimum number of events None

238

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Include endpoints None

238

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C3_HEART_MEDIASTINUM_PLEURA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 238 53 185
Unadjusted prevalence (%) 0.07 0.03 0.12
Mean age at first event (years) 66.86 57.53 69.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_HEART_MEDIASTINUM_PLEURA – Malignant neoplasm of heart, mediastinum and pleura
GWS hits:

Survival analyses between endpoints

Plot

before Malignant neoplasm of heart, mediastinum and pleura
after Malignant neoplasm of heart, mediastinum and pleura

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Drugs most likely to be purchased after Malignant neoplasm of heart, mediastinum and pleura