Alcoholic cardiomyopathy

CARMYOPATHALCO

alcoholic cardiomyopathy: Disease of CARDIAC MUSCLE resulting from chronic excessive alcohol consumption. Myocardial damage can be caused by: (1) a toxic effect of alcohol; (2) malnutrition in alcoholics such as THIAMINE DEFICIENCY; or (3) toxic effect of additives in alcoholic beverages such as COBALT. This disease is usually manifested by DYSPNEA and palpitations with CARDIOMEGALY and congestive heart failure (HEART FAILURE).

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I42.6
Hospital discharge: ICD-9 4255
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I42.6
Cause of death: ICD-9 4255
Cause of death: ICD-8 $!$

122

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

122

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Check minimum number of events None

122

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Include endpoints None

122

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CARMYOPATHALCO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I42
Name in latin Cardiomyopathia alcoholica

Summary Statistics

Key figures

All Female Male
Number of individuals 122 12 110
Unadjusted prevalence (%) 0.03 0.01 0.07
Mean age at first event (years) 58.50 50.61 59.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CARMYOPATHALCO – Alcoholic cardiomyopathy
GWS hits:

Survival analyses between endpoints

Plot

before Alcoholic cardiomyopathy
after Alcoholic cardiomyopathy

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Drugs most likely to be purchased after Alcoholic cardiomyopathy