Cardiomyopathy

I9_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I42
Cause of death: ICD-10 I42

5187

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

5187

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Check minimum number of events None

5187

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I9_CARDMYO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I30-I52
Name in latin Cardiomyopathia

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 5480 1768 3712
Unadjusted prevalence (%) 1.54 0.89 2.36
Mean age at first event (years) 59.33 57.79 60.06

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.38 [3.97, 7.28] 1.6e-27 1281
15 years 0.02 2.44 [1.79, 3.33] 1.9e-8 497
5 years 0.01 4.83 [3.93, 5.96] 1.1e-49 371
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CARDMYO – Cardiomyopathy
GWS hits: 13

Survival analyses between endpoints

Plot

before Cardiomyopathy
after Cardiomyopathy

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