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Multiple myeloma and malignant plasma cell neoplasms

DOID EFO MESH PheWeb

CD2_MULTIPLE_MYELOMA_PLASMA_CELL

multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 C90
Hospital discharge: ICD-9 203
Hospital discharge: ICD-8 203
Cause of death: ICD-10 C90
Cause of death: ICD-9 203
Cause of death: ICD-8 203

1122

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1122

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Check minimum number of events None

1122

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Include endpoints None

1122

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CD2_MULTIPLE_MYELOMA_PLASMA_CELL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF8
Parent code in ICD-10 C81-C96
Name in latin Myeloma multiplex et neoplasmata maligna plasmacytorum

Summary Statistics

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Key figures

All Female Male
Number of individuals 1122 505 617
Unadjusted prevalence (%) 0.32 0.25 0.39
Mean age at first event (years) 66.01 64.62 67.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL – Multiple myeloma and malignant plasma cell neoplasms
GWS hits:

Survival analyses between endpoints

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Plot

before Multiple myeloma and malignant plasma cell neoplasms
after Multiple myeloma and malignant plasma cell neoplasms

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Drugs most likely to be purchased after Multiple myeloma and malignant plasma cell neoplasms

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