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Other and unspecified types of non-Hodgkin lymphoma

DOID EFO MESH PheWeb

CD2_NONHODGKIN_NAS

non-Hodgkins lymphoma: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 C85
Hospital discharge: ICD-9 200[8-9]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 C85
Cause of death: ICD-9 200[8-9]
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

1012

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CD2_NONHODGKIN_NAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF8
Parent code in ICD-10 C81-C96
Name in latin Typi alii et non specificati lymphomatis non-Hodgkin

Summary Statistics

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Key figures

All Female Male
Number of individuals 1012 427 585
Unadjusted prevalence (%) 0.28 0.22 0.37
Mean age at first event (years) 61.78 59.59 63.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.36 [1.85, 6.10] 6.7e-5 290
15 years 0.01 1.25 [0.79, 1.99] 3.5e-1 65
5 years 0.01 4.22 [2.95, 6.02] 2.4e-15 74
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_NONHODGKIN_NAS – Other and unspecified types of non-Hodgkin lymphoma
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified types of non-Hodgkin lymphoma
after Other and unspecified types of non-Hodgkin lymphoma

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Drugs most likely to be purchased after Other and unspecified types of non-Hodgkin lymphoma

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