Cholelithiasis, broad definition with cholecystitis

CHOLELITH_BROAD

cholelithiasis: The presence of calculi in the gallbladder.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

35607

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CHOLELITH_BROAD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 35607 23638 11969
Unadjusted prevalence (%) 10.01 11.91 7.61
Mean age at first event (years) 52.31 48.68 59.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.43 [1.26, 1.62] 1.4e-8 5101
15 years 0.01 0.98 [0.88, 1.08] 6.4e-1 2152
5 years 0.00 1.67 [1.52, 1.84] 4.2e-27 1092
1 year 0.00 5.12 [4.53, 5.79] <1e-100 625

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHOLELITH_BROAD – Cholelithiasis, broad definition with cholecystitis
GWS hits: 71

Survival analyses between endpoints

Plot

before Cholelithiasis, broad definition with cholecystitis
after Cholelithiasis, broad definition with cholecystitis

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Drugs most likely to be purchased after Cholelithiasis, broad definition with cholecystitis