Diseases of the digestive system

XI_DIGESTIVE

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K00-K93, K77.0*B96.8
Hospital discharge: ICD-9 5[2-7]
Hospital discharge: ICD-8 5[2-7]
Cause of death: ICD-10 K00-K93, K77.0*B96.8
Cause of death: ICD-9 5[2-7]
Cause of death: ICD-8 5[2-7]

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

189010

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XI_DIGESTIVE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 189010 99389 89621
Unadjusted prevalence (%) 53.13 50.09 56.95
Mean age at first event (years) 46.07 44.05 48.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.05 [1.92, 2.19] <1e-100 23114
15 years 0.01 1.33 [1.24, 1.42] 1.8e-16 9627
5 years 0.00 2.24 [2.10, 2.40] <1e-100 4866
1 year 0.00 7.47 [6.70, 8.33] <1e-100 2969

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: XI_DIGESTIVE – Diseases of the digestive system
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the digestive system
after Diseases of the digestive system

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Drugs most likely to be purchased after Diseases of the digestive system