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Agranulocytosis

DOID MESH PheWeb

D3_AGRANULOCYTOSIS

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D70
Hospital discharge: ICD-9 2880
Hospital discharge: ICD-8 2889
Cause of death: ICD-10 D70
Cause of death: ICD-9 2880
Cause of death: ICD-8 2889

3010

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3003

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Check minimum number of events None

3003

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Include endpoints None

3003

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D3_AGRANULOCYTOSIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D70-D77
Name in latin Agranulocytosis

Similar endpoints

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List of similar endpoints to Agranulocytosis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 3003 1920 1083
Unadjusted prevalence (%) 0.84 0.97 0.69
Mean age at first event (years) 56.82 55.02 59.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.17 11.04 [4.36, 27.96] 4.1e-7 598
15 years 0.02 2.32 [1.19, 4.53] 1.4e-2 77
5 years 0.02 16.54 [11.44, 23.93] 3.4e-50 205
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_AGRANULOCYTOSIS – Agranulocytosis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Agranulocytosis
after Agranulocytosis

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