Drug-induced neutropenia

DRUGADVERS_NEUTROPENIA

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D70.82#

1840

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10

1840

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Check minimum number of events None

1840

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Include endpoints None

1840

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DRUGADVERS_NEUTROPENIA

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 1840 1190 650
Unadjusted prevalence (%) 0.52 0.60 0.41
Mean age at first event (years) 59.39 57.90 62.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.40 30.24 [18.76, 48.74] 1.7e-44 408
15 years 0.02 3.50 [2.04, 5.99] 5.0e-6 46
5 years 0.02 15.26 [9.57, 24.34] 2.7e-30 131
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: DRUGADVERS_NEUTROPENIA – Drug-induced neutropenia
GWS hits:

Survival analyses between endpoints

Plot

before Drug-induced neutropenia
after Drug-induced neutropenia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Drug-induced neutropenia