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Other and unspecified coagulation defects

DOID EFO MESH SNOMED PheWeb

D3_COAGDEFNAS

blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D68.8, D68.9
Hospital discharge: ICD-9 2869
Hospital discharge: ICD-8 2869
Cause of death: ICD-10 D68.8, D68.9
Cause of death: ICD-9 2869
Cause of death: ICD-8 2869

1106

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1106

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Check minimum number of events None

1106

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Include endpoints None

1106

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D3_COAGDEFNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified coagulation defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1106 782 324
Unadjusted prevalence (%) 0.31 0.39 0.21
Mean age at first event (years) 46.63 43.80 53.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.49 [2.12, 9.50] 8.9e-5 79
15 years 0.02 2.07 [0.97, 4.42] 5.9e-2 29
5 years 0.01 3.79 [1.86, 7.73] 2.5e-4 23
1 year 0.00 16.91 [8.37, 34.15] 3.1e-15 22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGDEFNAS – Other and unspecified coagulation defects
GWS hits: 19

Survival analyses between endpoints

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Plot

before Other and unspecified coagulation defects
after Other and unspecified coagulation defects

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified coagulation defects

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