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Other coagulation defects

DOID EFO MESH SNOMED PheWeb

D3_COAGOTHER

thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D68
Cause of death: ICD-10 D68

1712

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1712

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Check minimum number of events None

1712

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Include endpoints

1746

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D3_COAGOTHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D65-D69
Name in latin Aliae defectus coagulationis

Similar endpoints

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List of similar endpoints to Other coagulation defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1746 1173 573
Unadjusted prevalence (%) 0.49 0.59 0.36
Mean age at first event (years) 48.74 44.25 57.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 10.12 [5.08, 20.17] 4.8e-11 249
15 years 0.02 2.58 [1.43, 4.65] 1.6e-3 42
5 years 0.01 6.31 [4.04, 9.84] 4.7e-16 35
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGOTHER – Other coagulation defects
GWS hits: 19

Survival analyses between endpoints

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Plot

before Other coagulation defects
after Other coagulation defects

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Drugs most likely to be purchased after Other coagulation defects

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