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Immunodeficiency with predominantly antibody defects

DOID MESH PheWeb

D3_IMMUDEFANTIBODY

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 D80
Cause of death: ICD-10 D80

651

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

651

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Check minimum number of events None

651

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Include endpoints

669

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D3_IMMUDEFANTIBODY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D80-D89
Name in latin Deficientia immunalis praecipue cum vitiis anticorporum

Similar endpoints

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List of similar endpoints to Immunodeficiency with predominantly antibody defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 669 439 230
Unadjusted prevalence (%) 0.19 0.22 0.15
Mean age at first event (years) 46.25 45.97 46.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.29 [1.68, 16.68] 4.5e-3 61
15 years 0.02 3.34 [1.21, 9.21] 2.0e-2 22
5 years 0.02 12.08 [5.82, 25.07] 2.3e-11 24
1 year 0.01 27.18 [12.34, 59.87] 2.5e-16 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUDEFANTIBODY – Immunodeficiency with predominantly antibody defects
GWS hits:

Survival analyses between endpoints

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Plot

before Immunodeficiency with predominantly antibody defects
after Immunodeficiency with predominantly antibody defects

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Drugs most likely to be purchased after Immunodeficiency with predominantly antibody defects

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