Certain disorders involving the immune mechanism

DOID EFO MESH SNOMED PheWeb

D3_IMMUNEMECHANISM

immune system disease: A disorder resulting from an abnormality in the immune system.

Endpoint definition

↥

FinnGen phenotype data

356077 individuals

Apply sex-specific rule None

356077

Check conditions None

356077

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

D3_IMMUDEFANTIBODY

D3_COMBIMMUDEF

D3_IMMUDEFWITHMAJORDEF

D3_CVID

D3_IMMUDEFOTHER

D3_KELA_IMMUDEF

D3_SARCOIDOSIS

D3_IMMUNEMECHANISMOTHER

5547

D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Certain disorders involving the immune mechanism based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	5547	3055	2492
Unadjusted prevalence (%)	1.56	1.54	1.58
Mean age at first event (years)	47.15	46.83	47.55

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.57 [1.11, 2.21]	1.1e-2	506
15 years	0.01	1.01 [0.74, 1.37]	9.6e-1	189
5 years	0.00	2.29 [1.71, 3.05]	1.7e-8	116
1 year	0.00	7.42 [5.38, 10.25]	3.2e-34	68

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: D3_IMMUNEMECHANISM – Certain disorders involving the immune mechanism
GWS hits: 8

Survival analyses between endpoints

↥

Plot

before Certain disorders involving the immune mechanism
after Certain disorders involving the immune mechanism

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Certain disorders involving the immune mechanism

↥

≡ Risteys

R8

R7

R6

R5

R4

R3