≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

AION (anterior ischemic optic neuropathy)

DOID MESH PheWeb

DM_AION

No definition available.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H47.0
Hospital discharge: ICD-9 3774
Hospital discharge: ICD-8 37799
Cause of death: ICD-10 H47.0
Cause of death: ICD-9 3774
Cause of death: ICD-8 37799

444

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

444

diagram downward connector

Check minimum number of events None

444

diagram downward connector

Include endpoints None

444

diagram downward connector
DM_AION

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 H47
Name in latin Morbositates nervi optici non alibi classificatae

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 444 229 215
Unadjusted prevalence (%) 0.12 0.12 0.14
Mean age at first event (years) 58.80 55.92 61.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.49 [1.91, 6.38] 4.7e-5 58
15 years 0.01 1.43 [0.70, 2.91] 3.3e-1 22
5 years 0.00 2.00 [0.86, 4.64] 1.1e-1 16
1 year 0.00 8.06 [3.42, 18.99] 1.8e-6 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: DM_AION – AION (anterior ischemic optic neuropathy)
GWS hits:

Survival analyses between endpoints

↥

Plot

before AION (anterior ischemic optic neuropathy)
after AION (anterior ischemic optic neuropathy)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after AION (anterior ischemic optic neuropathy)

↥