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Diabetic hypoglycemia

DOID EFO MESH SNOMED PheWeb

DM_HYPOGLYC

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E10.00, E11.00, E16.0#, E16.2
Hospital discharge: ICD-9 2510B|2512
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E10.00, E11.00, E16.0#, E16.2
Cause of death: ICD-9 2510B|2512
Cause of death: ICD-8 $!$

6700

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6700

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Check minimum number of events None

6700

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Include endpoints None

6700

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DM_HYPOGLYC

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 6700 2746 3954
Unadjusted prevalence (%) 1.88 1.38 2.51
Mean age at first event (years) 54.56 51.14 56.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 6.65 [5.40, 8.20] 6.4e-71 2077
15 years 0.02 3.17 [2.65, 3.80] 2.9e-36 814
5 years 0.01 6.15 [5.39, 7.02] <1e-100 709
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_HYPOGLYC – Diabetic hypoglycemia
GWS hits: 4

Survival analyses between endpoints

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Plot

before Diabetic hypoglycemia
after Diabetic hypoglycemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic hypoglycemia

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