Endocrine, nutritional and metabolic diseases

IV_ENDOCRIN_NUTRIT

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E00-E90
Hospital discharge: ICD-9 2[4-7]
Hospital discharge: ICD-8 2[4-7]
Cause of death: ICD-10 E00-E90
Cause of death: ICD-9 2[4-7]
Cause of death: ICD-8 2[4-7]

119865

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

107378

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Check minimum number of events None

107378

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Include endpoints None

107378

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IV_ENDOCRIN_NUTRIT

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 107378 59413 47965
Unadjusted prevalence (%) 30.18 29.95 30.48
Mean age at first event (years) 53.74 50.62 57.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.36 [3.10, 3.64] <1e-100 15832
15 years 0.01 1.98 [1.84, 2.14] 1.3e-71 6339
5 years 0.00 3.65 [3.42, 3.90] <1e-100 4415
1 year 0.00 12.18 [11.07, 13.40] <1e-100 3093

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: IV_ENDOCRIN_NUTRIT – Endocrine, nutritional and metabolic diseases
GWS hits:

Survival analyses between endpoints

Plot

before Endocrine, nutritional and metabolic diseases
after Endocrine, nutritional and metabolic diseases

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Drugs most likely to be purchased after Endocrine, nutritional and metabolic diseases