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Diabetic maculopathy

DOID EFO MESH SNOMED PheWeb

DM_MACULOPATHY

macular degeneration: Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H36.01*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H36.01*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

3212

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3212

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Check minimum number of events None

3212

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Include endpoints None

3212

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DM_MACULOPATHY

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3212 1302 1910
Unadjusted prevalence (%) 0.90 0.66 1.21
Mean age at first event (years) 52.43 50.72 53.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 6.01 [4.74, 7.62] 1.1e-49 582
15 years 0.03 3.59 [2.89, 4.46] 8.0e-31 300
5 years 0.01 5.00 [4.00, 6.23] 5.1e-46 181
1 year 0.00 5.58 [3.93, 7.91] 5.2e-22 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_MACULOPATHY – Diabetic maculopathy
GWS hits:

Survival analyses between endpoints

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Plot

before Diabetic maculopathy
after Diabetic maculopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic maculopathy

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