Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)

DM_VITREOUS_BLEEDING

neovascular glaucoma: Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H43.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H43.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

2533

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2533

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Check minimum number of events None

2533

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Include endpoints None

2533

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DM_VITREOUS_BLEEDING

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 H43
Name in latin Haemorrhagia corporis vitrei

Summary Statistics

Key figures

All Female Male
Number of individuals 2533 1202 1331
Unadjusted prevalence (%) 0.71 0.61 0.85
Mean age at first event (years) 58.11 57.38 58.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.86 [3.39, 6.96] 7.4e-18 380
15 years 0.02 2.68 [1.93, 3.72] 3.1e-9 187
5 years 0.01 4.28 [3.23, 5.68] 5.9e-24 121
1 year 0.00 5.71 [3.83, 8.51] 1.4e-17 33

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: DM_VITREOUS_BLEEDING – Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)
GWS hits: 1

Survival analyses between endpoints

Plot

before Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)
after Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)

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Drugs most likely to be purchased after Vitreous bleeding (caused by prolif. dmrp when together with H36.03*)