Disorders of vitreous body and globe

H7_VITREOUS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H43-H45
Cause of death: ICD-10 H43-H45

13716

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

13716

diagram downward connector

Check minimum number of events None

13716

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

13895

diagram downward connector
H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Disorders of vitreous body and globe based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 13895 8697 5198
Unadjusted prevalence (%) 3.91 4.38 3.30
Mean age at first event (years) 61.82 61.10 63.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.65 [1.29, 2.11] 5.8e-5 1036
15 years 0.01 1.13 [0.93, 1.37] 2.3e-1 523
5 years 0.00 2.03 [1.70, 2.42] 1.9e-15 312
1 year 0.00 3.11 [2.42, 4.00] 9.1e-19 88

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_VITREOUS – Disorders of vitreous body and globe
GWS hits:

Survival analyses between endpoints

Plot

before Disorders of vitreous body and globe
after Disorders of vitreous body and globe

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of vitreous body and globe