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Marasmic kwashiorkor

DOID EFO MESH SNOMED PheWeb

E4_MARAKWASH

kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning 'displaced child'. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E42
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E42
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

53

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

53

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Check minimum number of events None

53

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Include endpoints None

53

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E4_MARAKWASH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E40-E46
Name in latin Malnutritio gravis ex deficientia proteino-energetica

Summary Statistics

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Key figures

All Female Male
Number of individuals 53 33 20
Unadjusted prevalence (%) 0.01 0.02 0.01
Mean age at first event (years) 45.91 45.57 46.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_MARAKWASH – Marasmic kwashiorkor
GWS hits:

Survival analyses between endpoints

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Plot

before Marasmic kwashiorkor
after Marasmic kwashiorkor

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Marasmic kwashiorkor

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