Testicular hypofunction

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only males

157571

diagram downward connector

Check conditions None

157571

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E29.1#
Hospital discharge: ICD-9 257[1-2]
Hospital discharge: ICD-8 2571
Cause of death: ICD-10 E29.1#
Cause of death: ICD-9 257[1-2]
Cause of death: ICD-8 2571
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E29.1#

95767

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

513

diagram downward connector

Check minimum number of events None

513

diagram downward connector

Include endpoints None

513

diagram downward connector
E4_TESTICHYPO

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E29
Name in latin Hypofunctio testium

Summary Statistics

Key figures

All Female Male
Number of individuals 513 - 513
Unadjusted prevalence (%) 0.14 - 0.33
Mean age at first event (years) 49.03 - 49.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.33 [1.83, 10.23] 8.5e-4 24
15 years 0.02 2.40 [0.97, 5.98] 5.9e-2 11
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_TESTICHYPO – Testicular hypofunction
GWS hits:

Survival analyses between endpoints

Plot

before Testicular hypofunction
after Testicular hypofunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Testicular hypofunction