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Disorders of other endocrine glands

DOID EFO MESH SNOMED PheWeb

E4_ENDOGLAND

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E20-E35
Cause of death: ICD-10 E20-E35

10478

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

10451

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Check minimum number of events None

10451

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Include endpoints

13931

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E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 13931 9440 4491
Unadjusted prevalence (%) 3.92 4.76 2.85
Mean age at first event (years) 48.52 47.14 51.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.44 [1.97, 3.01] 1.4e-16 1726
15 years 0.01 1.50 [1.27, 1.77] 1.4e-6 763
5 years 0.00 2.55 [2.19, 2.96] 6.6e-34 493
1 year 0.00 5.79 [4.81, 6.97] 1.4e-76 216

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDOGLAND – Disorders of other endocrine glands
GWS hits: 4

Survival analyses between endpoints

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Plot

before Disorders of other endocrine glands
after Disorders of other endocrine glands

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Drugs most likely to be purchased after Disorders of other endocrine glands

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