≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Thyrotoxicosis with toxic multinodular goitre

DOID EFO MESH SNOMED PheWeb

E4_THYTOXGOITMULT

Toxic Nodular Goiter: Nodular enlargement of the thyroid gland associated with hyperthyroidism.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E05.2
Hospital discharge: ICD-9 2422
Hospital discharge: ICD-8 2421
Cause of death: ICD-10 E05.2
Cause of death: ICD-9 2422
Cause of death: ICD-8 2421

1559

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1447

diagram downward connector

Check minimum number of events None

1447

diagram downward connector

Include endpoints None

1447

diagram downward connector
E4_THYTOXGOITMULT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E05
Name in latin Thyreotoxicosis cum struma multinodulari

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1447 1170 277
Unadjusted prevalence (%) 0.41 0.59 0.18
Mean age at first event (years) 57.56 56.37 62.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.35 [0.70, 2.58] 3.7e-1 153
15 years 0.01 0.87 [0.51, 1.49] 6.2e-1 56
5 years 0.00 2.11 [1.34, 3.33] 1.3e-3 38
1 year 0.00 4.22 [2.29, 7.75] 3.7e-6 15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_THYTOXGOITMULT – Thyrotoxicosis with toxic multinodular goitre
GWS hits: 12

Survival analyses between endpoints

↥

Plot

before Thyrotoxicosis with toxic multinodular goitre
after Thyrotoxicosis with toxic multinodular goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Thyrotoxicosis with toxic multinodular goitre

↥