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Autism

DOID EFO MESH PheWeb

F5_AUTISM

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F84.0, F84.1, F84.5
Hospital discharge: ICD-9 2990
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F84.0, F84.1, F84.5
Cause of death: ICD-9 2990
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

538

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F5_AUTISM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 538 225 313
Unadjusted prevalence (%) 0.15 0.11 0.20
Mean age at first event (years) 24.31 25.62 23.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.87 119.26 [50.44, 281.94] 1.3e-27 11
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_AUTISM – Autism
GWS hits:

Survival analyses between endpoints

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Plot

before Autism
after Autism

loading spinner Loading survival analyses plot