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Any mental disorder

DOID EFO MESH SNOMED PheWeb

KRA_PSY_ANYMENTAL

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F0[0-3]|F051|G30|F[1-9]
Hospital discharge: ICD-9  29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A 
Hospital discharge: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310
Cause of death: ICD-10 F0[0-3]|F051|G30|F[1-9]
Cause of death: ICD-9  29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A 
Cause of death: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310

90858

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

90705

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Check minimum number of events None

90705

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Include endpoints

91048

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KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 91048 51473 39575
Unadjusted prevalence (%) 25.59 25.94 25.15
Mean age at first event (years) 43.43 40.98 46.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.54 [4.16, 4.95] <1e-100 13448
15 years 0.01 2.39 [2.20, 2.60] 8.2e-92 4272
5 years 0.01 5.32 [4.95, 5.71] <1e-100 4161
1 year 0.00 16.87 [15.32, 18.58] <1e-100 3175

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_ANYMENTAL – Any mental disorder
GWS hits: 17

Survival analyses between endpoints

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Plot

before Any mental disorder
after Any mental disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Any mental disorder

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