Any mental disorder


vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 F0[0-3]|F051|G30|F[1-9]
Hospital discharge: ICD-9  29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A 
Hospital discharge: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310
Cause of death: ICD-10 F0[0-3]|F051|G30|F[1-9]
Cause of death: ICD-9  29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A 
Cause of death: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 91048 51473 39575
Unadjusted prevalence (%) 25.59 25.94 25.15
Mean age at first event (years) 43.43 40.98 46.61


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.54 [4.16, 4.95] <1e-100 13448
15 years 0.01 2.39 [2.20, 2.60] 8.2e-92 4272
5 years 0.01 5.32 [4.95, 5.71] <1e-100 4161
1 year 0.00 16.87 [15.32, 18.58] <1e-100 3175

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: KRA_PSY_ANYMENTAL – Any mental disorder
GWS hits: 17

Survival analyses between endpoints


before Any mental disorder
after Any mental disorder

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Drugs most likely to be purchased after Any mental disorder