Mental retardation


mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 F70-F79
Cause of death: ICD-10 F70-F79


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1208 573 635
Unadjusted prevalence (%) 0.34 0.29 0.40
Mean age at first event (years) 25.02 25.61 24.48


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.11 [1.41, 6.86] 5.1e-3 132
15 years 0.02 2.21 [1.12, 4.36] 2.2e-2 57
5 years 0.00 2.88 [1.41, 5.88] 3.7e-3 19
1 year 0.00 10.18 [4.71, 22.01] 3.7e-9 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: F5_MENTRET – Mental retardation
GWS hits:

Survival analyses between endpoints


before Mental retardation
after Mental retardation

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Drugs most likely to be purchased after Mental retardation