Other and unspecified mental retardation

F5_OTHRET

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F78, F79
Hospital discharge: ICD-9 3199
Hospital discharge: ICD-8 315
Cause of death: ICD-10 F78, F79
Cause of death: ICD-9 3199
Cause of death: ICD-8 315

708

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

421

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Check minimum number of events None

421

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Include endpoints None

421

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F5_OTHRET

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 421 190 231
Unadjusted prevalence (%) 0.12 0.10 0.15
Mean age at first event (years) 20.22 21.88 18.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.27 [2.37, 11.71] 4.5e-5 32
15 years 0.02 3.34 [1.31, 8.51] 1.1e-2 16
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_OTHRET – Other and unspecified mental retardation
GWS hits:

Survival analyses between endpoints

Plot

before Other and unspecified mental retardation
after Other and unspecified mental retardation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified mental retardation