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Post-traumatic stress disorder

DOID EFO MESH SNOMED PheWeb

F5_PTSD

post-traumatic stress disorder: An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F43.1
Hospital discharge: ICD-9 3098X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F43.1
Cause of death: ICD-9 3098X
Cause of death: ICD-8 $!$

2100

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2100

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Check minimum number of events None

2100

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Include endpoints None

2100

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F5_PTSD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F43
Name in latin Perturbatio stressualis posttraumatica

Summary Statistics

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Key figures

All Female Male
Number of individuals 2100 1699 401
Unadjusted prevalence (%) 0.59 0.86 0.25
Mean age at first event (years) 35.71 34.84 39.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.97 [2.17, 7.26] 7.6e-6 49
15 years 0.02 2.36 [1.20, 4.63] 1.3e-2 26
5 years 0.00 3.70 [1.54, 8.88] 3.4e-3 13
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_PTSD – Post-traumatic stress disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Post-traumatic stress disorder
after Post-traumatic stress disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Post-traumatic stress disorder

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