Mental and behavioural disorders due to tobacco

F5_TOBAC

nicotine dependence: Physical and psychological dependence on nicotine.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F17
Hospital discharge: ICD-9 3051
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F17
Cause of death: ICD-9 3051
Cause of death: ICD-8 $!$

2006

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1976

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Check minimum number of events None

1976

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Include endpoints None

1976

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F5_TOBAC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu tabaci

Summary Statistics

Key figures

All Female Male
Number of individuals 1976 992 984
Unadjusted prevalence (%) 0.56 0.50 0.63
Mean age at first event (years) 54.82 51.44 58.22

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 9.58 [5.26, 17.43] 1.5e-13 282
15 years 0.03 3.84 [2.12, 6.95] 9.4e-6 99
5 years 0.02 11.96 [8.25, 17.35] 4.4e-39 122
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_TOBAC – Mental and behavioural disorders due to tobacco
GWS hits:

Survival analyses between endpoints

Plot

before Mental and behavioural disorders due to tobacco
after Mental and behavioural disorders due to tobacco

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Drugs most likely to be purchased after Mental and behavioural disorders due to tobacco